With the advancement of medical science, scientists have been gaining a deeper understanding of disease mechanisms and physiological processes, leading to the continuous emergence of advanced diagnostic and therapeutic techniques. To continually improve patients’ outcomes and quality of life, and to extend survival, medical scientists and pharmacologists are relentless in their pursuit of new drug development. This is particularly evident in the fields of rare diseases, cancer, and metabolic diseases, where significant investments are made.

Clinical trials are a crucial part of the new drug development and treatment method innovation process, used to assess the safety and efficacy of new drugs and therapies. For certain diseases, especially rare diseases, cancer, and refractory conditions, clinical trials may offer new options beyond existing treatments, potentially yielding better outcomes than traditional methods. Patients participating in trials typically receive closer medical monitoring and support than in standard treatments, ensuring their health and safety. Moreover, by participating in clinical trials, patients can access the latest medical information and research developments regarding their conditions. Additionally, since the drug development duration is long (averaging 8-10 years) and requires regulatory approval before market release, patients can engage with new drugs before they are available, avoiding long waiting periods. Most patients involved in new drug clinical trials can receive free trial-related medications, special examinations, and financial compensation according to the study protocol. This is particularly beneficial for many newly launched, expensive drugs (such as anticancer medications), significantly alleviating the financial burden on families.

To participate in a clinical trial, individuals must first meet the inclusion criteria, such as age, gender, diagnosed disease, comorbidities or symptoms, and treatment history. Patients also need to sign an informed consent form, indicating their understanding of the trial's purpose, procedures, and risks. Throughout the trial, participants are required to follow the study protocol for treatment and related medical assessments.